Aljona Saleh

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 529 citations

Medicine, Cancer Biology, Oncology +4

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Marcus J.G.W. Ladds, Ingeborg M.M. van Leeuwen, Catherine J. Drummond et al. · Nature Communications · 2018 · 92 citations · Full text

Medicine, Oncology, Pharmacology +13

Evaluation of a direct high-capacity target screening approach for urine drug testing using liquid chromatography–time-of-flight mass spectrometry

Aljona Saleh, Niclas Nikolai Stephanson, Ingrid Granelli et al. · Journal of Chromatography B · 2012 · 39 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +14

Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability

Gergana Popova, Marcus J.G.W. Ladds, Lars Johansson et al. · Journal of Medicinal Chemistry · 2020 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma

Aljona Saleh, Camilla Göktürk, Ulrika Warpman Berglund et al. · Journal of Pharmaceutical and Biomedical Analysis · 2014 · 14 citations

Pharmacy, Pharmacokinetics, Pharmacology +7