Stereocontrolled Total Synthesis of (+)-Vinblastine

Satoshi Yokoshima, Toshihiro Ueda, Satoshi Kobayashi, +4

Journal of the American Chemical Society

Stereocontrolled Total SynthesisNovel Indole SynthesisDiversity-oriented SynthesisNatural SciencesTotal Synthesis +8

Properties of Ga_1-xIn_xN Films Prepared by MOVPE

Takao Nagatomo, Takeshi Kuboyama, Hiroyuki Minamino, +1

Japanese Journal of Applied Physics

Materials EngineeringMaterials ScienceIi-vi SemiconductorOptical MaterialsEngineering +11

Stereocontrolled total synthesis of (+)-vincristine

Takeshi Kuboyama, Satoshi Yokoshima, Hidetoshi Tokuyama, +1

Proceedings of the National Academy of Sciences

A Novel Transformation of Primary Amines to N-Monoalkylhydroxylamines

Hidetoshi Tokuyama, Takeshi Kuboyama, Akiko Amano, +1

Synthesis

M-cpba OxidationEngineeringOrganic ChemistryCatalysisSynthetic Chemistry +7

Stereocontrolled total synthesis of (+)-vinblastine

Satoshi Yokoshima, Toshihiro Ueda, Satoshi Kobayashi, +4

Pure and Applied Chemistry

Diversity Oriented SynthesisNatural Product SynthesisDerivativesBioorganic ChemistryEngineering +13

In vivo activation of PEGylated long circulating lipid nanoparticle to achieve efficient siRNA delivery and target gene knock down in solid tumors

Yumi Sasayama, Maki Hasegawa, Eri Taguchi, +9

Journal of Controlled Release

NanoparticlesNanomedicineEfficient Sirna DeliveryEngineeringTargeted Drug Delivery +9

Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles

Motoi Nakahara, Takeshi Kuboyama, Akihiro Izawa, +3

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryBase-pairing PropertiesOligonucleotideMolecular Biology

Quantitative evaluation of the improvement in the pharmacokinetics of a nucleic acid drug delivery system by dynamic PET imaging with 18F-incorporated oligodeoxynucleotides

Hidefumi Mukai, Daiki Ozaki, Yilong Cui, +11

Journal of Controlled Release

Positron Emission TomographyQuantitative EvaluationEngineeringMedical ImagingPet-mri +10

Pharmacokinetic evaluation of liposomal nanoparticle-encapsulated nucleic acid drug: A combined study of dynamic PET imaging and LC/MS/MS analysis

Hidefumi Mukai, Kentaro Hatanaka, Nobuhiro Yagi, +10

Journal of Controlled Release

NanomedicinePharmacokinetic EvaluationEngineeringLc/ms/ms AnalysisImaging Agent +6

Development of Dihydrodibenzooxepine Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Ligands of a Novel Binding Mode as Anticancer Agents: Effective Mimicry of Chiral Structures by Olefinic <i>E</i>/<i>Z</i>-Isomers

Keisuke Yamamoto, Tomohiro Tamura, Kazuki Henmi, +8

Journal of Medicinal Chemistry