Kevin N. Cobley

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4<i>H</i>-pyran-6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Journal of Medicinal Chemistry · 1998 · 343 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 55 citations

Life Sciences, Biochemistry, Medicinal Chemistry +13

Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase

David C. Humber, N. Cammack, Jonathan A. Coates et al. · Journal of Medicinal Chemistry · 1992 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

A series of penicillin-derived C2-symmetric inhibitors of HIV-1 proteinase: synthesis, mode of interaction, and structure-activity relationships

David C. Humber, Mark J. Bamford, Richard C. Bethell et al. · Journal of Medicinal Chemistry · 1993 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and Biological Activity of Novel Cephalosporins Containing a (Z)-Vinyl Dimethylphosphonate Group.

Paul W. Smith, Albert Jaxa Chamiec, Gavin A.C. Chung et al. · The Journal of Antibiotics · 1995 · 23 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +11