Concepedia

Karen McGovern

KM

32

Publications

8.5K

Citations

24

H-Index

1991

Active since

Affiliations

Infinity Pharmaceuticals (United States)(Current)

Harvard University

Hospital for Sick Children

Mount Sinai Hospital

Cleveland Clinic

Karen McGovern is an author at Infinity Pharmaceuticals (United States) specializing in medicine, pharmacology, and cell biology.

Top concepts

MedicineCell BiologyPharmacologyTumor BiologyDrug DiscoveryCancer BiologyCancer ResearchOncologyImmunologyCancer Therapy

Publications per year

1991–2023

32

Publications

32

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson et al. · Science · 2009 · 3.1K citations · Full text

Tumor Biology, Oncology, Pancreatic Cancer +12

PI3Kγ is a molecular switch that controls immune suppression

Megan M. Kaneda, Karen Messer, Natacha Ralainirina et al. · Nature · 2016 · 1.1K citations · Full text

Molecular Immunology, Immune Regulation, Immunology +6

Identification of a protein required for disulfide bond formation in vivo

James C.A. Bardwell, Karen McGovern, J Beckwith · Cell · 1991 · 978 citations

Proteinlipid Interaction, Protein Secretion, Protein Function +6

Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

Olivier De Henau, Matthew Rausch, David A. Winkler et al. · Nature · 2016 · 843 citations

Hematological Malignancy, Blockade Therapy, Immunology +7

Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine

Luís Felipe Campesato, Sadna Budhu, Jeremy H. Tchaicha et al. · Nature Communications · 2020 · 418 citations · Full text

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