Josef Leibold

Senolytic CAR T cells reverse senescence-associated pathologies

Corina Amor, Judith Feucht, Josef Leibold et al. · Nature · 2020 · 968 citations · Full text

T-regulatory Cell, Immunology, Cellular Senescence +5

Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency

Judith Feucht, Jie Sun, Justin Eyquem et al. · Nature Medicine · 2018 · 512 citations · Full text

Signal Transduction, Adaptive Immune System, T-regulatory Cell +8

NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

Marcus Ruscetti, Josef Leibold, Matthew J. Bott et al. · Science · 2018 · 416 citations · Full text

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

Marcus Ruscetti, John P. Morris, Riccardo Mezzadra et al. · Cell · 2020 · 392 citations · Full text

Pancreatic Cancer, Pancreas Cancer, Cellular Senescence +6

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

Ramona Rudalska, Daniel Dauch, Thomas Longerich et al. · Nature Medicine · 2014 · 276 citations · Full text

Tumor Biology, Systems Biology, Engineering +13