Ivan Kopljar

Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels

Eva Cuypers, Yousra Abdel–Mottaleb, Ivan Kopljar et al. · Toxicon · 2008 · 87 citations · Full text

Life Sciences, Biology, Physiology +16

Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking

Ivan Kopljar, Hua Rong Lu, Karel Van Ammel et al. · Stem Cell Reports · 2018 · 59 citations · Full text

Medicine, Cardiology, Pharmacology +16

Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Ivan Kopljar, David J. Gallacher, An De Bondt et al. · Stem Cells Translational Medicine · 2016 · 56 citations · Full text

Medicine, Cardiology, Pharmacology +15

Chronic drug‐induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell‐derived cardiomyocytes

Ivan Kopljar, An De Bondt, Petra Vinken et al. · British Journal of Pharmacology · 2017 · 52 citations · Full text

Medicine, Cardiology, Pharmacology +14

A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol

Ivan Kopljar, Alain J. Labro, Eva Cuypers et al. · Proceedings of the National Academy of Sciences · 2009 · 49 citations

Natural Sciences, Biophysics, Pharmacology +17