D.E. Puleo

Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight

B. Barry Touré, J. Giraldes, Troy Smith et al. · Journal of Medicinal Chemistry · 2016 · 51 citations · Full text

Selective Inhibitors, Cell Cycle, Preliminary Biology Insight +17

Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies

Kanak Raina, Chris D. Forbes, Rebecca Stronk et al. · Cell chemical biology · 2024 · 50 citations · Full text

Tumor Biology, Drug Targeting, Medicine +13

Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants

Kathleen M. Frey, D.E. Puleo, Krasimir A. Spasov et al. · Journal of Medicinal Chemistry · 2015 · 47 citations · Full text

Molecular Biology, Peptide Science, Antiviral Drug +19

Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders

D.E. Puleo, Kaury Kucera, Henrik M. Hammarén et al. · ACS Medicinal Chemistry Letters · 2017 · 45 citations · Full text

Janus Kinases, Immunology, Molecular Biology +23

Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively

Kanak Raina, Chris D. Forbes, Rebecca Stronk et al. · 2023 · 33 citations · Full text