Michael Vrkljan

Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor

Shashi Kumar Gupta, Masao Hirota, Sheela Waugh et al. · Journal of Biological Chemistry · 2014 · 150 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs)

Mark J. Mulvihill, Julie L.C. Kan, Patricia Beck et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 16 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

Cutaneous mast cell degranulation in rats receiving injections of recombinant human interleukin-1 receptor antagonist (rhIL-1ra) and/or its vehicle: possible clinical implications.

A.M. Bendele, M. Colloton, Michael Vrkljan et al. · PubMed · 1995 · 13 citations

Medicine, Immunology, Pharmacology +16