Hidetoh Toki

Antidepressant Potential of (R)-Ketamine in Rodent Models: Comparison with (S)-Ketamine

Kenichi Fukumoto, Hidetoh Toki, Michihiko Iijima et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 245 citations

AMPA Receptor Activation–Independent Antidepressant Actions of Ketamine Metabolite (S)-Norketamine

Chun Yang, Shizuka Kobayashi, Kazuhito Nakao et al. · Biological Psychiatry · 2018 · 117 citations

Molecular Pharmacology, Ketamine Metabolite, Psychiatry +5

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice

Junichi Yamaguchi, Hidetoh Toki, Youge Qu et al. · Neuropsychopharmacology · 2018 · 104 citations · Full text

Molecular Pharmacology, Antidepressant Actions, Psychoactive Drug +10

A rapid and sensitive chiral LC–MS/MS method for the determination of ketamine and norketamine in mouse plasma, brain and cerebrospinal fluid applicable to the stereoselective pharmacokinetic study of ketamine

Hidetoh Toki, Takuya Ichikawa, Akiko Mizuno‐Yasuhira et al. · Journal of Pharmaceutical and Biomedical Analysis · 2017 · 43 citations

Medicine, Cerebrospinal Fluid, Mouse Plasma +8

Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model

Kai Zhang, Hidetoh Toki, Yūkō Fujita et al. · Psychopharmacology · 2018 · 31 citations

Antidepressant Effects, Psychiatry, Mood Symptom +13