Akiko Mizuno‐Yasuhira

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice

Junichi Yamaguchi, Hidetoh Toki, Youge Qu et al. · Neuropsychopharmacology · 2018 · 104 citations · Full text

Molecular Pharmacology, Antidepressant Actions, Psychoactive Drug +10

A rapid and sensitive chiral LC–MS/MS method for the determination of ketamine and norketamine in mouse plasma, brain and cerebrospinal fluid applicable to the stereoselective pharmacokinetic study of ketamine

Hidetoh Toki, Takuya Ichikawa, Akiko Mizuno‐Yasuhira et al. · Journal of Pharmaceutical and Biomedical Analysis · 2017 · 43 citations

Medicine, Cerebrospinal Fluid, Mouse Plasma +8

Lack of deuterium isotope effects in the antidepressant effects of (R)-ketamine in a chronic social defeat stress model

Kai Zhang, Hidetoh Toki, Yūkō Fujita et al. · Psychopharmacology · 2018 · 31 citations

Antidepressant Effects, Psychiatry, Mood Symptom +13

No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model

Lijia Chang, Hidetoh Toki, Youge Qu et al. · The International Journal of Neuropsychopharmacology · 2018 · 26 citations · Full text

Metabolite profiling and enzyme reaction phenotyping of luseogliflozin, a sodium–glucose cotransporter 2 inhibitor, in humans

Atsunori Miyata, Masatoshi Hasegawa, Kenji Hachiuma et al. · Xenobiotica · 2016 · 22 citations

Sodium–glucose Cotransporter 2, Metabolomic Profiling, Primary Metabolic Pathways +21