Kenichi Fukumoto

Antidepressant Potential of (R)-Ketamine in Rodent Models: Comparison with (S)-Ketamine

Kenichi Fukumoto, Hidetoh Toki, Michihiko Iijima et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 245 citations

Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2<i>R</i>,6<i>R</i>)-hydroxynorketamine

Kenichi Fukumoto, Manoela V. Fogaça, Rong-Jian Liu et al. · Proceedings of the National Academy of Sciences · 2018 · 180 citations · Full text

The Antidepressant Effects of an mGlu2/3 Receptor Antagonist and Ketamine Require AMPA Receptor Stimulation in the mPFC and Subsequent Activation of the 5-HT Neurons in the DRN

Kenichi Fukumoto, Michihiko Iijima, Shigeyuki Chaki · Neuropsychopharmacology · 2015 · 169 citations · Full text

Mglu2/3 Receptor Antagonist, Antidepressant Effects, Psychiatry +12

Serotonin-1A receptor stimulation mediates effects of a metabotropic glutamate 2/3 receptor antagonist, 2S-2-amino-2-(1S,2S-2-carboxycycloprop-1-yl)-3-(xanth-9-yl)propanoic acid (LY341495), and an N-methyl-D-aspartate receptor antagonist, ketamine, in the novelty-suppressed feeding test

Kenichi Fukumoto, Michihiko Iijima, Shigeyuki Chaki · Psychopharmacology · 2014 · 101 citations

Psychiatry, Medicine, Receptor Antagonist +9

Role of BDNF/TrkB signaling in antidepressant-like effects of a group II metabotropic glutamate receptor antagonist in animal models of depression

Hiroyuki Koike, Kenichi Fukumoto, Michihiko Iijima et al. · Behavioural Brain Research · 2012 · 93 citations

Psychiatry, Mood Symptom, Antidepressant-like Effects +10