Daniele Fancelli

PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer

Patrizia Carpinelli, Roberta Ceruti, Maria Laura Giorgini et al. · Molecular Cancer Therapeutics · 2007 · 240 citations

Histone H3, Potent Inhibitor, Cancer Biology +16

1,4,5,6-Tetrahydropyrrolo[3,4-<i>c</i>]pyrazoles:  Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile

Daniele Fancelli, Jürgen Moll, Mario Varasi et al. · Journal of Medicinal Chemistry · 2006 · 189 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Chemoprevention Strategy +14

PHA-680632, a Novel Aurora Kinase Inhibitor with Potent Antitumoral Activity

Chiara Soncini, Patrizia Carpinelli, Laura Gianellini et al. · Clinical Cancer Research · 2006 · 160 citations

Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition

Daniele Fancelli, Daniela Berta, Simona Bindi et al. · Journal of Medicinal Chemistry · 2005 · 143 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +18

Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor PHA-739358

Michèle Modugno, Elena Casale, Chiara Soncini et al. · Cancer Research · 2007 · 132 citations · Full text

Hematological Malignancy, Tumor Biology, Kinase Domain +15