Jürgen Moll

A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity

Alessia Montagnoli, Barbara Valsasina, Valter Croci et al. · Nature Chemical Biology · 2008 · 215 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase

Riccardo Colombo, Marina Caldarelli, Milena Mennecozzi et al. · Cancer Research · 2010 · 201 citations · Full text

Medicine, Cancer Biology, Oncology +17

1,4,5,6-Tetrahydropyrrolo[3,4-<i>c</i>]pyrazoles:  Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile

Daniele Fancelli, Jürgen Moll, Mario Varasi et al. · Journal of Medicinal Chemistry · 2006 · 190 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

Inhibition of protein–protein interactions: The discovery of druglike β‐catenin inhibitors by combining virtual and biophysical screening

Jean‐Yves Trosset, Claudio Dalvit, Stefan Knapp et al. · Proteins Structure Function and Bioinformatics · 2006 · 181 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I

Artur Gontarewicz, Stefan Balabanov, Gunhild Keller et al. · Blood · 2008 · 166 citations · Full text

Medicine, Oncology, Pharmacology +11