María Elena Romero

Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB.

Xuezhong Yang, Melinda S. Merchant, María Elena Romero et al. · PubMed · 2003 · 96 citations

Life Sciences, Cell Biology, Oncology +17

Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2.

Vassiliki Poulaki, Nicholas Mitsiades, María Elena Romero et al. · PubMed · 2001 · 77 citations

Life Sciences, Cell Biology, Oncology +17

Interferon γ Enhances the Effectiveness of Tumor Necrosis Factor-Related Apoptosis–Inducing Ligand Receptor Agonists in a Xenograft Model of Ewing’s Sarcoma

Melinda S. Merchant, Xuezhong Yang, Fraia Melchionda et al. · Cancer Research · 2004 · 73 citations

Medicine, Oncology, Pharmacology +17

Interferon-γ Sensitizes Resistant Ewing's Sarcoma Cells to Tumor Necrosis Factor Apoptosis-Inducing Ligand-Induced Apoptosis by Up-Regulation of Caspase-8 Without Altering Chemosensitivity

Andrej Lissat, Thomas Vraetz, Maria Tsokos et al. · American Journal Of Pathology · 2007 · 41 citations · Full text

Life Sciences, Cancer Biology, Oncology +16