Derek R. Laver

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

Hiroshi Watanabe, Nagesh Chopra, Derek R. Laver et al. · Nature Medicine · 2009 · 596 citations · Full text

Cardiac Muscle, Cardiomyopathy, Cardiovascular Disease +8

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass

Fredrick A. Hilliard, Derek S. Steele, Derek R. Laver et al. · Journal of Molecular and Cellular Cardiology · 2009 · 238 citations · Full text

Molecular Physiology, Signal Transduction, Biochemistry +8

Magnesium Inhibition of Ryanodine-Receptor Calcium Channels: Evidence for Two Independent Mechanisms

Derek R. Laver, Tim Baynes, Angela F. Dulhunty · The Journal of Membrane Biology · 1997 · 193 citations

Molecular Pharmacology, Molecular Physiology, Magnesium Inhibition +11

Cytoplasmic Ca2+ inhibits the ryanodine receptor from cardiac muscle

Derek R. Laver, Lennart Rodén, Gerard P. Ahern et al. · The Journal of Membrane Biology · 1995 · 171 citations

Cardiac Muscle, Signal Transduction, Molecular Physiology +7

Calsequestrin Is an Inhibitor of Skeletal Muscle Ryanodine Receptor Calcium Release Channels

Nicole A. Beard, Magdalena M. Sakowska, Angela F. Dulhunty et al. · Biophysical Journal · 2002 · 170 citations · Full text

Molecular Pharmacology, Muscle Function, Molecular Physiology +10