Nagesh Chopra

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

Hiroshi Watanabe, Nagesh Chopra, Derek R. Laver et al. · Nature Medicine · 2009 · 596 citations · Full text

Cardiac Muscle, Cardiomyopathy, Cardiovascular Disease +8

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass

Fredrick A. Hilliard, Derek S. Steele, Derek R. Laver et al. · Journal of Molecular and Cellular Cardiology · 2009 · 238 citations · Full text

Molecular Physiology, Signal Transduction, Biochemistry +8

Ablation of triadin causes loss of cardiac Ca ²⁺ release units, impaired excitation–contraction coupling, and cardiac arrhythmias

Nagesh Chopra, Tao Yang, Parisa Asghari et al. · Proceedings of the National Academy of Sciences · 2009 · 155 citations · Full text

Cardiac Muscle, Molecular Biology, Impaired Excitation–contraction Coupling +24

Striking In Vivo Phenotype of a Disease-Associated Human <i>SCN5A</i> Mutation Producing Minimal Changes in Vitro

Hiroshi Watanabe, Tao Yang, Dina Myers Stroud et al. · Circulation · 2011 · 139 citations · Full text

Modest Reductions of Cardiac Calsequestrin Increase Sarcoplasmic Reticulum Ca ²⁺ Leak Independent of Luminal Ca ²⁺ and Trigger Ventricular Arrhythmias in Mice

Nagesh Chopra, Prince J. Kannankeril, Tao Yang et al. · Circulation Research · 2007 · 130 citations

Cardiac Muscle, Heart Failure, Cellular Physiology +16