Joan A. Zugay

L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor.

Joseph P. Vacca, Bruce D. Dorsey, William A. Schleif et al. · Proceedings of the National Academy of Sciences · 1994 · 526 citations

Medicine, Pharmacokinetics, Pharmacology +17

L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

Bruce D. Dorsey, Rhonda B. Levin, Joseph P. Vacca et al. · Journal of Medicinal Chemistry · 1994 · 411 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl design

Wayne J. Thompson, Paula M.D. Fitzgerald, M. Katharine Holloway et al. · Journal of Medicinal Chemistry · 1992 · 167 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13

Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors

Terry A. Lyle, Catherine M. Wiscount, James P. Guare et al. · Journal of Medicinal Chemistry · 1991 · 97 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Nonpeptidal P₂ Ligands for HIV Protease Inhibitors:  Structure-Based Design, Synthesis, and Biological Evaluation

Arun K. Ghosh, John Kincaid, D. Eric Walters et al. · Journal of Medicinal Chemistry · 1996 · 96 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16