R. Chris Bleackley

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B

Alison J. Darmon, Donald W. Nicholson, R. Chris Bleackley · Nature · 1995 · 723 citations

Apoptotic Protease Cpp32, Signal Transduction, Protein Function +13

Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis

Bruce Motyka, Gregory S. Korbutt, Michael J. Pinkoski et al. · Cell · 2000 · 386 citations · Full text

Apoptosis, Immune Regulation, Immunology +8

Granzyme B Short-Circuits the Need for Caspase 8 Activity during Granule-Mediated Cytotoxic T-Lymphocyte Killing by Directly Cleaving Bid

Michèle Barry, Jeffrey A. Heibein, Michael J. Pinkoski et al. · Molecular and Cellular Biology · 2000 · 335 citations · Full text

Mitophagy, Apoptosis, Immunology +19

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

Joanna Bagińska, Elodie Viry, Guy Berchem et al. · Proceedings of the National Academy of Sciences · 2013 · 321 citations · Full text

Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax

Jeffrey A. Heibein, Ing Swie Goping, Michèle Barry et al. · The Journal of Experimental Medicine · 2000 · 304 citations · Full text

Mitophagy, Signal Transduction, Molecular Physiology +13