Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase

Yanyan Zhao, Weiwei Jiang, Bin Li, +8

International Immunopharmacology

Tumor BiologyOncogenic AgentMedicineG2/m PhaseCell Cycle Arrest +6

Dual Role of Triptolide in Interrupting the NLRP3 Inflammasome Pathway to Attenuate Cardiac Fibrosis

Xichun Pan, Ya Liu, Yanyan Cen, +7

International Journal of Molecular Sciences

Artesunate attenuated progression of atherosclerosis lesion formation alone or combined with rosuvastatin through inhibition of pro-inflammatory cytokines and pro-inflammatory chemokines

Weiwei Jiang, Yanyan Cen, Yi Song, +6

Phytomedicine

InflammationThrombosisVascular DiseaseCardiovascular DiseaseMedicine +9

Artesunate in combination with oxacillin protect sepsis model mice challenged with lethal live methicillin-resistant Staphylococcus aureus (MRSA) via its inhibition on proinflammatory cytokines release and enhancement on antibacterial activity of oxacillin

Weiwei Jiang, Bin Li, Xinchuan Zheng, +7

International Immunopharmacology

InflammationAnti-inflammatoryHealth SciencesMedicineAntibacterial Activity +11

Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin.

Yu Liu, Benhua Zeng, Haitao Shang, +2

PubMed

Bama Miniature PigsLovastatin MetabolismSus Scrofa DomesticaLaboratory Animal StudyPharmacological Study +18

The direct anti-MRSA effect of emodin via damaging cell membrane

Ming Liu, Wei Peng, Rongxin Qin, +8

Applied Microbiology and Biotechnology

Cell MembraneBiochemistryMedicinePharmacologyOxidative Stress +1

Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity

Feng Cao, Wei Peng, Xiao‐Li Li, +9

Canadian Journal of Physiology and Pharmacology

Medicinal ChemistryAntifungal AgentBiochemistryBioassay-guided IsolationMedicine +12

Magnesium isoglycyrrhizinate ameliorates radiation-induced pulmonary fibrosis by inhibiting fibroblast differentiation via the p38MAPK/Akt/Nox4 pathway

Qunfang Yang, Pan Zhang, Tao Liu, +6

Biomedicine & Pharmacotherapy

Artesunate ameliorates severe acute pancreatitis (SAP) in rats by inhibiting expression of pro-inflammatory cytokines and Toll-like receptor 4

Yanyan Cen, Chao Liu, Xiaoli Li, +8

International Immunopharmacology

InflammationAnti-inflammatoryPro-inflammatory CytokinesMedicineImmunology +7

Artesunate Attenuates Pro-Inflammatory Cytokine Release from Macrophages by Inhibiting TLR4-Mediated Autophagic Activation via the TRAF6-Beclin1-PI3KC3 Pathway

Mei Kuang, Yanyan Cen, Rongxin Qin, +5

Cellular Physiology and Biochemistry