David Karis

Creating Novel Activated Factor XI Inhibitors through Fragment Based Lead Generation and Structure Aided Drug Design

Ola Fjellström, Sibel Akkaya, Hans‐Georg Beisel et al. · PLoS ONE · 2015 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A new series of pyridinyl-alkynes as antagonists of the metabotropic glutamate receptor 5 (mGluR5)

Peter Bach, Karolina Nilsson, Andreas Wållberg et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 31 citations · Full text

Life Sciences, Medicinal Chemistry, Neuroscience +13

Structure–activity relationships for the linker in a series of pyridinyl-alkynes that are antagonists of the metabotropic glutamate receptor 5 (mGluR5)

Peter Bach, Karolina Nilsson, Tor Svensson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation—Structure‐Based Hit Evaluation and Chemistry Exploration

Yafeng Xue, Thomas Olsson, Carina Johansson et al. · ChemMedChem · 2016 · 16 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17