Concepedia

Jonathan Chang

JC

23

Publications

1.6K

Citations

18

H-Index

2006

Active since

Affiliations

Genomics Institute of the Novartis Research Foundation(Current)

Georgia Institute of Technology

Emory University

The Wallace H. Coulter Department of Biomedical Engineering

The Ohio State University

Jonathan Chang is an author at Genomics Institute of the Novartis Research Foundation specializing in medicine, drug discovery, and pharmacology.

ORCID

Top concepts

Publications per year

2006–2022

23

Publications

23

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 405 citations · Full text

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Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation

Xiaorong Zhu, Jeannette S. Messer, Yunwei Wang et al. · Journal of Clinical Investigation · 2015 · 195 citations · Full text

TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts

Angelo L. Grauel, Beverly Nguyen, David A. Ruddy et al. · Nature Communications · 2020 · 191 citations · Full text

A small molecule accelerates neuronal differentiation in the adult rat

Heiko Wurdak, Shoutian Zhu, Kyung Hoon Min et al. · Proceedings of the National Academy of Sciences · 2010 · 117 citations · Full text

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Imidazolopiperazines: Hit to Lead Optimization of New Antimalarial Agents

Tao Wu, A. S. Nagle, Kelli Kuhen et al. · Journal of Medicinal Chemistry · 2011 · 103 citations · Full text

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