Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

Adel Samson, Karen J. Scott, David J. Taggart, +36

Science Translational Medicine

Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling

Maurice Kléber, Hye-Youn Lee, Heiko Wurdak, +6

The Journal of Cell Biology

SclerostinAdult Stem CellCombinatorial WntSynaptic SignalingSensory Neurogenesis +21

A Small Molecule Primes Embryonic Stem Cells for Differentiation

Shoutian Zhu, Heiko Wurdak, Jian Wang, +5

Cell stem cell

Embryonic Stem CellDevelopmental BiologyCell SpecializationMedicineAdult Stem Cell +7

Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery

Saira Alli, Carlyn A. Figueiredo, Brian Golbourn, +11

Journal of Controlled Release

Medical UltrasoundFocused UltrasoundNeurophysiologyMedicineDoxorubicin Delivery +9

Inactivation of TGFβ signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

Heiko Wurdak, Lars M. Ittner, Karl S. Lang, +6

Genes & Development

Brain Area-Specific Effect of TGF-β Signaling on Wnt-Dependent Neural Stem Cell Expansion

Sven Falk, Heiko Wurdak, Lars M. Ittner, +13

Cell stem cell

NeuroregenerationDevelopmental BiologyBrain DevelopmentMedicineStem Cell Research +7

RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells

Harry O. King, Tim Brend, Helen L. Payne, +8

Stem Cell Reports

Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells

Lars M. Ittner, Heiko Wurdak, Schwerdtfeger Kerstin, +9

Journal of Biology

An RNAi Screen Identifies TRRAP as a Regulator of Brain Tumor-Initiating Cell Differentiation

Heiko Wurdak, Shoutian Zhu, Angélica Romero, +16

Cell stem cell

Developmental BiologyCell RegulationMedicineTumor SuppressorGene Expression +4

Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord

Fabian Ille, Suzana Atanasoski, Sven Falk, +7

Developmental Biology

NeuroregenerationDevelopmental BiologyBone Morphogenic ProteinDorsal Spinal CordNeuroanatomy +9