Daniel Chubb

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Claire Palles, Jean‐Baptiste Cazier, Kimberley Howarth et al. · Nature Genetics · 2012 · 986 citations · Full text

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

Yufei Wang, James McKay, Zhaoming Wang et al. · Nature Genetics · 2014 · 472 citations · Full text

Cancer Risk, Rare Variants, Medicine +8

Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine.

M. F. G. STEVENS, J A Hickman, S P Langdon et al. · PubMed · 1987 · 390 citations

Antitumor Activity, Pharmacotherapy, Metronomic Chemotherapy +17

Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group

D. Mandelker, Mark T.A. Donoghue, Sabrina Talukdar et al. · Annals of Oncology · 2019 · 231 citations · Full text

Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer

Daniel Chubb, Peter Broderick, Sara E. Dobbins et al. · Nature Communications · 2016 · 166 citations · Full text