A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells

Joseph Collin, Rachel Queen, Darin Zerti, +20

The Ocular Surface

Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface

Joseph Collin, Rachel Queen, Darin Zerti, +10

The Ocular Surface

Deconstructing Retinal Organoids: Single Cell RNA-Seq Reveals the Cellular Components of Human Pluripotent Stem Cell-Derived Retina

Joseph Collin, Rachel Queen, Darin Zerti, +5

Stem Cells

An integrated transcriptional analysis of the developing human retina

Carla Mellough, Roman Bauer, Joseph Collin, +16

Development

Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences

Carla Mellough, Joseph Collin, Rachel Queen, +7

Stem Cells Translational Medicine

Cell DifferentiationOptogeneticsCell SpecializationSystematic ComparisonRegenerative Medicine +17

Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids

Birthe Dorgau, Majed Felemban, Gerrit Hilgen, +13

Biomaterials

Cerebral OrganoidOptogeneticsRegenerative MedicineGanglion CellRetina +18

CRX Expression in Pluripotent Stem Cell-Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones

Joseph Collin, Darin Zerti, Rachel Queen, +10

Stem Cells

Transplanted Pluripotent Stem Cell-Derived Photoreceptor Precursors Elicit Conventional and Unusual Light Responses in Mice With Advanced Retinal Degeneration

Darin Zerti, Gerrit Hilgen, Birthe Dorgau, +5

Stem Cells

Host RetinaRetinal TherapiesOptogeneticsRegenerative MedicineGanglion Cell +17

Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell-derived retinal organoids

Darin Zerti, Birthe Dorgau, Majed Felemban, +5

Stem Cells

Ocular DiseaseRetinoic AcidCell Replacement TherapyRetinal TherapiesStem Cell Biology +19

Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix

Majed Felemban, Birthe Dorgau, Nicola C. Hunt, +11

Acta Biomaterialia