A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Lars G. Fritsche, Wilmar Igl, Jessica N. Cooke Bailey, +158

Nature Genetics

Genome-wide Association StudyOcular DiseaseOphthalmologyGeneticsAge-related Diseases +4

A saturated map of common genetic variants associated with human height

Loïc Yengo, Sailaja Vedantam, Eirini Marouli, +572

Nature

ILC1 Confer Early Host Protection at Initial Sites of Viral Infection

Orr-El Weizman, Nicholas M. Adams, Iona S. Schuster, +7

Cell

Host ResponseHost FactorViral PersistenceInitial SitesPathogenesis +8

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

Kathryn P. Burdon, Stuart MacGregor, Alex W. Hewitt, +22

Nature Genetics

Genome-wide Association StudyAllelic VariantEngineeringMedicineGenetics +6

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot, Yingchang Lu, Heather M. Highland, +379

Nature Genetics

ObesityMetabolic SyndromeNutritionEnergy HomeostasisMetabolic Disorder +8

Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization

Katrina Spilsbury, Kerryn L. Garrett, Wei-Yong Shen, +2

American Journal Of Pathology

Developmental BiologyOphthalmologyChoroidal NeovascularizationVascular BiologyGlaucoma +6

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

G. Bragi Walters, Alex W. Hewitt, Gísli Másson, +43

Nature Genetics

Ocular DiseaseGeneticsPathologyGlaucomaCommon Variants +3

CIS is a potent checkpoint in NK cell–mediated tumor immunity

Rebecca B. Delconte, Tatiana B. Kolesnik, Laura F. Dagley, +29

Nature Immunology

Cancer ImmunosurveillanceImmunologyTumor ImmunityImmune Checkpoint InhibitorCellular Immune Response +3

Visual Acuity Is Correlated with the Area of the Foveal Avascular Zone in Diabetic Retinopathy and Retinal Vein Occlusion

Chandrakumar Balaratnasingam, Maiko Inoue, Seungjun Ahn, +4

Ophthalmology

Diabetic RetinopathyOcular DiseaseRetinaOphthalmologyDiabetes +4

The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss

Lyndon da Cruz, Brian Coley, Jessy D. Dorn, +10

British Journal of Ophthalmology