Ioannis Assiotis

Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity

Ilirjana Bajrami, Jessica Frankum, Asha Konde et al. · Cancer Research · 2013 · 361 citations · Full text

Engineering, Molecular Biology, Pathology +23

Secondary mutations in <i><scp>BRCA2</scp></i> associated with clinical resistance to a <scp>PARP</scp> inhibitor

Louise J. Barber, Shahneen Sandhu, Lina Chen et al. · The Journal of Pathology · 2012 · 334 citations

Engineering, Genetics, Pathology +18

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

Nicola H. Dryden, Laura R. Broome, Frank Dudbridge et al. · Genome Research · 2014 · 263 citations · Full text

A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies Parp1 as a Mediator of Olaparib Toxicity

Stephen J. Pettitt, Farah Rehman, Ilirjana Bajrami et al. · PLoS ONE · 2013 · 174 citations · Full text

Genome Instability, Olaparib Toxicity, Piggybac Transposon +14

Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen

Ana M. Mendes‐Pereira, David Sims, Tim Dexter et al. · Proceedings of the National Academy of Sciences · 2011 · 147 citations