Pascale Vicat

Improved antibacterial activities of coumarin antibiotics bearing 5′,5′-dialkylnoviose: biological activity of RU79115

Branislav Musicki, Anne‐Marie Periers, Patrick Laurin et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 125 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3<i>S</i>)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7<i>H</i>-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

Youssef El‐Ahmad, Michel Tabart, Frank Halley et al. · Journal of Medicinal Chemistry · 2019 · 81 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 43 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10

Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo

Antonello Pessi, Sandra L. Bixler, Veronica Soloveva et al. · Antiviral Research · 2019 · 36 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +16

Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models

Delphine Valente, Christine Mauriac, Thorsten Schmidt et al. · mAbs · 2020 · 32 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17