Laura Prado

Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin

Laura Prado, Ernestina Fernández, Ulrike Weiβbach et al. · Chemistry & Biology · 1999 · 86 citations · Full text

Antitumor Drug Mithramycin, Medicinal Chemistry, Biosynthesis +11

Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus

Laura Prado, Felipe Lombó, Alfredo F. Braña et al. · Molecular and General Genetics MGG · 1999 · 58 citations

Biosynthesis, Streptomyces Argillaceus, Chromosomal Regions +5

The mtmVUC genes of the mithramycin gene cluster in Streptomycesargillaceus are involved in the biosynthesis of the sugar moieties

Aída González, Lily L. Remsing, Felipe Lombó et al. · Molecular Genetics and Genomics · 2001 · 48 citations · Full text

Biosynthesis, Sugar Moieties, Molecular Biology +5

The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin

Felipe Lombó, Eva Künzel, Laura Prado et al. · Angewandte Chemie International Edition · 2000 · 29 citations

Engineering, Genetics, Molecular Biology +20

The structures of premithramycinone and demethylpremithramycinone, plausible early intermediates of the aureolic acid group antibiotic mithramycin

Jürgen Rohr, Ulrike Weißbach, Claus Beninga et al. · Chemical Communications · 1998 · 25 citations · Full text

Bioorganic Chemistry, Organic Chemistry, Plausible Early Intermediates +17