Jürgen Rohr

Combinatorial biosynthesis of antitumor indolocarbazole compounds

César Sánchez, Alfredo F. Braña, Aaroa P. Salas et al. · Proceedings of the National Academy of Sciences · 2004 · 246 citations · Full text

Pharmacy, Biological Engineering, Biotechnology +17

Identification of Two Genes from <i>Streptomyces argillaceus</i> Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

Ernestina Fernández, Ulrike Weißbach, César Sánchez Reillo et al. · Journal of Bacteriology · 1998 · 226 citations · Full text

Life Sciences, Biochemistry, Microbiology +12

The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin

César Sánchez, Igor A. Butovich, Alfredo F. Braña et al. · Chemistry & Biology · 2002 · 218 citations · Full text

Medicine, Molecular Biology, Pharmacology +8

Facile Chemoenzymatic Strategies for the Synthesis and Utilization of<i>S</i>‐Adenosyl‐<scp>L</scp>‐Methionine Analogues

Shanteri Singh, Jianjun Zhang, Tyler D. Huber et al. · Angewandte Chemie International Edition · 2014 · 152 citations

Life Sciences, Biochemistry, Biotechnology +13

Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration

Sama F. Sleiman, Brett Langley, Manuela Basso et al. · Journal of Neuroscience · 2011 · 141 citations · Full text

Medicine, Molecular Biology, Oncology +17