Sama F. Sleiman

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

Sama F. Sleiman, Jeffrey Henry, Rami Al-Haddad et al. · eLife · 2016 · 775 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Lactate mediates the effects of exercise on learning and memory through SIRT1-dependent activation of hippocampal brain-derived neurotrophic factor (BDNF)

Lauretta El Hayek, Mohamad Khalifeh, Victor Zibara et al. · Journal of Neuroscience · 2019 · 514 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease

Stephen J. McConoughey, Manuela Basso, Zoya Niatsetskaya et al. · EMBO Molecular Medicine · 2010 · 142 citations · Full text

Life Sciences, Genetics, Neuroscience +16

Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration

Sama F. Sleiman, Brett Langley, Manuela Basso et al. · Journal of Neuroscience · 2011 · 141 citations · Full text

Medicine, Molecular Biology, Oncology +17

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Saravanan S. Karuppagounder, Ishraq Alim, Soah J. Khim et al. · Science Translational Medicine · 2016 · 140 citations · Full text

Medicine, Neurobiology, Neuroscience +15