Ralf Lotz

8-(3-(<i>R</i>)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes

Matthias Eckhardt, Elke Langkopf, Michael Mark et al. · Journal of Medicinal Chemistry · 2007 · 281 citations · Full text

Pharmaceutical Science, Xanthine Scaffold, Pharmacotherapy +17

Design, Synthesis, and Evaluation of Indolinones as Triple Angiokinase Inhibitors and the Discovery of a Highly Specific 6-Methoxycarbonyl-Substituted Indolinone (BIBF 1120)

Gerald J. Roth, Armin Heckel, Florian Colbatzky et al. · Journal of Medicinal Chemistry · 2009 · 229 citations · Full text

Combinatorial Chemistry, Chemoprevention Strategy, Triple Angiokinase Inhibitors +21

Structure elucidation of yersiniabactin, a siderophore from highly virulent <i>Yersinia</i> strains

Hartmut Drechsel, Holger Stephan, Ralf Lotz et al. · Liebigs Annalen · 1995 · 119 citations

Bioorganic Chemistry, Microbial Pathogens, Bacteriology +18

Discovery of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24 h bronchodilatory efficacy

Thierry Bouyssou, Christoph Hoenke, K Rudolf et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 79 citations · Full text

Characterization of the GI transit conditions in Beagle dogs with a telemetric motility capsule

Mirko Koziolek, Michael Grimm, Tabea Bollmann et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2019 · 62 citations

Animal Physiology, Veterinary Physiology, Working Dog +7