Armin Heckel

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

Silke Hauf, Richard W. Cole, Sabrina LaTerra et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

BIBF 1120: Triple Angiokinase Inhibitor with Sustained Receptor Blockade and Good Antitumor Efficacy

Frank Hilberg, Gerald J. Roth, Martin Krššák et al. · Cancer Research · 2008 · 1K citations · Full text

Triple Angiokinase Inhibitor, Chemoprevention Strategy, Pathology +18

Design, Synthesis, and Evaluation of Indolinones as Triple Angiokinase Inhibitors and the Discovery of a Highly Specific 6-Methoxycarbonyl-Substituted Indolinone (BIBF 1120)

Gerald J. Roth, Armin Heckel, Florian Colbatzky et al. · Journal of Medicinal Chemistry · 2009 · 229 citations · Full text

Combinatorial Chemistry, Chemoprevention Strategy, Triple Angiokinase Inhibitors +21

Crystal Structure of the Human Liver X Receptor β Ligand-binding Domain in Complex with a Synthetic Agonist

S. Hoerer, Angela Schmid, Armin Heckel et al. · Journal of Molecular Biology · 2003 · 75 citations

X-ray Crystallography, Molecular Pharmacology, Molecular Docking +9

BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport.

Hong Xing Chen, U. Bamberger, Armin Heckel et al. · PubMed · 1993 · 54 citations

Phenylpteridine Analogue, Molecular Biology, Tumor Cells +17