S. Hoerer

Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

Yange Niu, Rui Liu, Chengcheng Guan et al. · Nature · 2021 · 128 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +11

Crystal Structure of the Human Liver X Receptor β Ligand-binding Domain in Complex with a Synthetic Agonist

S. Hoerer, Angela Schmid, Armin Heckel et al. · Journal of Molecular Biology · 2003 · 75 citations

X-ray Crystallography, Molecular Pharmacology, Molecular Docking +9

Boosting antibody developability through rational sequence optimization

Daniel Seeliger, Patrick Schulz, Tobias Litzenburger et al. · mAbs · 2015 · 65 citations · Full text

Heuristic Sequence Analysis, Engineering, Rational Sequence Optimization +17

Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo

Christian A. Kuttruff, Marco Ferrara, Tom Bretschneider et al. · ACS Medicinal Chemistry Letters · 2017 · 42 citations · Full text

Antifibrotic Therapy, Pharmacotherapy, Experimental Pharmacology +19

Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule

Christofer S. Tautermann, Florian Binder, Frank Büttner et al. · Journal of Medicinal Chemistry · 2018 · 39 citations · Full text