Human chimeric antigen receptor macrophages for cancer immunotherapy

Michael Klichinsky, Marco Ruella, Olga Shestova, +23

Nature Biotechnology

Cancer ImmunosurveillanceImmunologyTumor ImmunityImmune Checkpoint InhibitorImmunotherapy +2

Use of Whole-Exome Sequencing to Determine the Genetic Basis of Multiple Mitochondrial Respiratory Chain Complex Deficiencies

Robert W. Taylor, Angela Pyle, Helen Griffin, +26

JAMA

CD137 Accurately Identifies and Enriches for Naturally Occurring Tumor-Reactive T Cells in Tumor

Qunrui Ye, De-Gang Song, Mathilde Poussin, +5

Clinical Cancer Research

Efficient and Accurate Quantitative Profiling of Alternative Splicing Patterns of Any Complexity on a Laptop

Timothy Sterne-Weiler, Robert J. Weatheritt, Andrew Best, +2

Molecular Cell

EngineeringGenomicsSequence AlignmentGene RecognitionSoftware Analysis +14

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Thomas Gonatopoulos-Pournatzis, Mingkun Wu, Ulrich Braunschweig, +11

Molecular Cell

Molecular NeuroscienceGenome-wide Crispr-cas9 InterrogationSyndromic AutismGeneticsRna Splicing +8

Chimeric NKG2D CAR-Expressing T Cell-Mediated Attack of Human Ovarian Cancer Is Enhanced by Histone Deacetylase Inhibition

De-Gang Song, Qunrui Ye, Stephen P. Santoro, +3

Human Gene Therapy

Activated T CellsCancer ImmunosurveillanceOncogenic AgentMedicineHistone Deacetylase Inhibition +10

Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development

Sushma Nagaraja Grellscheid, Caroline Dalgliesh, Markus Storbeck, +12

PLoS Genetics

Primary Human Ovarian Epithelial Cancer Cells Broadly Express HER2 at Immunologically-Detectable Levels

Evripidis Lanitis, Denarda Dangaj Laniti, Ian S. Hagemann, +5

PLoS ONE

Her2 ExpressionMedicineGynecologyPathologyCancer Genomics +9

Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons

Andrew Best, Katherine James, Caroline Dalgliesh, +17

Nature Communications

Expression of Tra2<b><i>β</i></b>in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis

Andrew Best, Caroline Dagliesh, Ingrid Ehrmann, +3

International Journal of Cell Biology

PathologyCancer BiologyTumor BiologyTranscriptional RegulationRegulator Proteins Srsf1 +16