Michael Klichinsky

Human chimeric antigen receptor macrophages for cancer immunotherapy

Michael Klichinsky, Marco Ruella, Olga Shestova et al. · Nature Biotechnology · 2020 · 1.3K citations · Full text

Cancer Immunosurveillance, Immunology, Tumor Immunity +4

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

Marco Ruella, Jun Xu, David M. Barrett et al. · Nature Medicine · 2018 · 620 citations · Full text

Autoimmune Disease, Immunology, Antigen Processing +5

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

Marco Ruella, David M. Barrett, Saad S. Kenderian et al. · Journal of Clinical Investigation · 2016 · 549 citations · Full text

Mixed-phenotype Acute Leukemia, Immunology, Immunoediting +22

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia

Miriam Kim, Kyung–Rok Yu, Saad S. Kenderian et al. · Cell · 2018 · 450 citations · Full text

Cell Therapy, Acute Myeloid Leukemia, Immunology +9

CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia

Saad S. Kenderian, Marco Ruella, Olga Shestova et al. · Leukemia · 2015 · 423 citations · Full text

Autoimmune Disease, T-regulatory Cell, Immunology +7