Liezl Gibhard

Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials

Jill M. Combrinck, Kim Y. Fong, Liezl Gibhard et al. · Malaria Journal · 2015 · 78 citations · Full text

Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel <i>Plasmodium falciparum</i> Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria

Nishanth Kandepedu, Diego González Cabrera, Srinivas Eedubilli et al. · Journal of Medicinal Chemistry · 2018 · 45 citations · Full text

Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages

Dina Coertzen, Janette Reader, Mariëtte van der Watt et al. · Antimicrobial Agents and Chemotherapy · 2018 · 42 citations · Full text

The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple <i>Plasmodium</i> kinases and life cycle stages

Lauren B. Arendse, James M. Murithi, Tarrick Qahash et al. · Science Translational Medicine · 2022 · 42 citations · Full text

Antimalarial Benzimidazole Derivatives Incorporating Phenolic Mannich Base Side Chains Inhibit Microtubule and Hemozoin Formation: Structure–Activity Relationship and <i>In Vivo</i> Oral Efficacy Studies

Godwin Akpeko Dziwornu, Dina Coertzen, Meta Leshabane et al. · Journal of Medicinal Chemistry · 2021 · 38 citations