Lauren B. Arendse

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Manu Vanaerschot, James M. Murithi, Charisse Flerida A. Pasaje et al. · Cell chemical biology · 2020 · 91 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +17

The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple <i>Plasmodium</i> kinases and life cycle stages

Lauren B. Arendse, James M. Murithi, Tarrick Qahash et al. · Science Translational Medicine · 2022 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structural Basis for Inhibitor Potency and Selectivity of <i>Plasmodium falciparum</i> Phosphatidylinositol 4-Kinase Inhibitors

Stephen Fienberg, Charles J. Eyermann, Lauren B. Arendse et al. · ACS Infectious Diseases · 2020 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design

Gyles E. Cozier, Lauren B. Arendse, Sylva L. U. Schwager et al. · Journal of Medicinal Chemistry · 2018 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension

Rhéure Alves-Lopes, Augusto C. Montezano, Karla B Neves et al. · Hypertension · 2021 · 25 citations · Full text

Medicine, Cardiology, Pharmacology +16