Takafumi Takai

Synthesis of a Novel Series of Tricyclic Dihydrofuran Derivatives: Discovery of 8,9-Dihydrofuro[3,2-<i>c</i>]pyrazolo[1,5-<i>a</i>]pyridines as Melatonin Receptor (MT₁/MT₂) Ligands

Tatsuki Koike, Takafumi Takai, Yasutaka Hoashi et al. · Journal of Medicinal Chemistry · 2011 · 63 citations · Full text

1,6-Dihydro-2<i>H</i>-indeno[5,4-<i>b</i>]furan Derivatives: Design, Synthesis, and Pharmacological Characterization of a Novel Class of Highly Potent MT₂-Selective Agonists

Tatsuki Koike, Yasutaka Hoashi, Takafumi Takai et al. · Journal of Medicinal Chemistry · 2011 · 47 citations · Full text

Pharmacological Characterization, Pharmacotherapy, Chemical Derivative +17

Discovery of a novel B-cell lymphoma 6 (BCL6)–corepressor interaction inhibitor by utilizing structure-based drug design

Takeshi Yasui, Takeshi Yamamoto, Nozomu Sakai et al. · Bioorganic & Medicinal Chemistry · 2017 · 38 citations · Full text

Drug Target, Medicine, Rational Drug Design +9

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists

Takuto Kojima, Michiyo Mochizuki, Takafumi Takai et al. · Bioorganic & Medicinal Chemistry · 2018 · 35 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Discovery of a Novel Series of<i>N</i>-Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase-2 Inhibitors

Kenjiro Sato, Hiroki Takahagi, Takeshi Yoshikawa et al. · Journal of Medicinal Chemistry · 2015 · 30 citations · Full text