Takuto Kojima

Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis.

Takuji Tanaka, Takuto Kojima, Masumi Suzui et al. · PubMed · 1993 · 105 citations

Tumor Biology, Oncology, Colon Carcinogenesis +15

Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode

Jun Fujimoto, Osamu Kurasawa, Terufumi Takagi et al. · ACS Medicinal Chemistry Letters · 2019 · 39 citations · Full text

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists

Takuto Kojima, Michiyo Mochizuki, Takafumi Takai et al. · Bioorganic & Medicinal Chemistry · 2018 · 35 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Chemoprevention of oral carcinogenesis by DL-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor: dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats.

Takuji Tanaka, Takuto Kojima, Akira Hara et al. · PubMed · 1993 · 33 citations

Chemoprevention Strategy, Pathology, Toxicological Mechanism +18

Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents

Takuto Kojima, Yasutomi Asano, Osamu Kurasawa et al. · Bioorganic & Medicinal Chemistry · 2018 · 23 citations · Full text

Cancer Therapeutic Agents, Medicine, Anti-cancer Agent +6