Julie K. Klint

Discovery of a selective Na _V 1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models

Shilong Yang, Yao Xiao, Di Kang et al. · Proceedings of the National Academy of Sciences · 2013 · 173 citations · Full text

Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional Analysis via Expression in the Periplasm of E. coli

Julie K. Klint, Sebastian Senff, Natalie J. Saez et al. · PLoS ONE · 2013 · 155 citations · Full text

Disulfide-rich Peptides, E. Coli, Bacterium Escherichia Coli +15

Seven novel modulators of the analgesic target <scp>Na_V</scp>1.7 uncovered using a high‐throughput venom‐based discovery approach

Julie K. Klint, Jennifer J. Smith, Irina Vetter et al. · British Journal of Pharmacology · 2015 · 81 citations · Full text

Discovery and Characterization of the Potent and Selective P2X4 Inhibitor <i>N</i> -[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile

Stefan Werner, Stefanie Mesch, R.C. Hillig et al. · Journal of Medicinal Chemistry · 2019 · 55 citations · Full text

Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7

Julie K. Klint, Yanni K.‐Y. Chin, Mehdi Mobli · Molecular Pharmacology · 2015 · 32 citations