Concepedia

Julie K. Klint

JK

8

Publications

554

Citations

8

H-Index

2013

Active since

Affiliations

The University of Queensland(Current)

Lundbeck (Denmark)

Julie K. Klint is an author at The University of Queensland specializing in molecular biology, natural sciences, and signal transduction.

Top concepts

Molecular BiologyMedicineNatural SciencesSignal TransductionBiophysicsEngineeringBiochemistryCell BiologyIon ChannelsCell Signaling

Publications per year

2013–2022

8

Publications

8

Discovery of a selective Na <sub>V</sub> 1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models

Shilong Yang, Yao Xiao, Di Kang et al. · Proceedings of the National Academy of Sciences · 2013 · 173 citations · Full text

Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional Analysis via Expression in the Periplasm of E. coli

Julie K. Klint, Sebastian Senff, Natalie J. Saez et al. · PLoS ONE · 2013 · 155 citations · Full text

Disulfide-rich Peptides, E. Coli, Bacterium Escherichia Coli +15

Seven novel modulators of the analgesic target <scp>Na<sub>V</sub></scp>1.7 uncovered using a high‐throughput venom‐based discovery approach

Julie K. Klint, Jennifer J. Smith, Irina Vetter et al. · British Journal of Pharmacology · 2015 · 81 citations · Full text

Discovery and Characterization of the Potent and Selective P2X4 Inhibitor <i>N</i> -[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile

Stefan Werner, Stefanie Mesch, R.C. Hillig et al. · Journal of Medicinal Chemistry · 2019 · 55 citations · Full text

Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7

Julie K. Klint, Yanni K.‐Y. Chin, Mehdi Mobli · Molecular Pharmacology · 2015 · 32 citations

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