Matthew M. Schuckmann

Amino Acid Mutation N348I in the Connection Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Multiclass Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors

Atsuko Hachiya, Eiichi Kodama, Stefan G. Sarafianos et al. · Journal of Virology · 2008 · 91 citations

Life Sciences, Molecular Biology, Pharmacology +17

The N348I Mutation at the Connection Subdomain of HIV-1 Reverse Transcriptase Decreases Binding to Nevirapine

Matthew M. Schuckmann, Bruno Marchand, Atsuko Hachiya et al. · Journal of Biological Chemistry · 2010 · 40 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

K70Q Adds High-Level Tenofovir Resistance to “Q151M Complex” HIV Reverse Transcriptase through the Enhanced Discrimination Mechanism

Atsuko Hachiya, Eiichi Kodama, Matthew M. Schuckmann et al. · PLoS ONE · 2011 · 29 citations · Full text

Life Sciences, Infectious Diseases, Pharmacotherapy +17

HIV-1 Reverse Transcriptase (RT) Polymorphism 172K Suppresses the Effect of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Non-nucleoside RT Inhibitors

Atsuko Hachiya, Bruno Marchand, Karen A. Kirby et al. · Journal of Biological Chemistry · 2012 · 10 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17