Hajime Toguchi

Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs

Jun-ichi Jinno, Naoki Kamada, Masateru Miyake et al. · Journal of Controlled Release · 2006 · 503 citations

Poorly Water-soluble Drug, Particle Size Reduction, Pharmacological Study +4

Preparation of Three-Month Depot Injectable Microspheres of Leuprorelin Acetate Using Biodegradable Polymers

Hiroaki Okada, Yayoi Doken, Yasuaki Ogawa et al. · Pharmaceutical Research · 1994 · 204 citations

In Vitro and in Vivo Evaluation of Mucoadhesive Microspheres Prepared for the Gastrointestinal Tract Using Polyglycerol Esters of Fatty Acids and a Poly(acrylic acid) Derivative

Yohko Akiyama, Naoki Nagahara, Toshio Kashihara et al. · Pharmaceutical Research · 1995 · 129 citations

Drug delivery using biodegradable microspheres

Hiroaki Okada, Yamamoto Masaki, Toshiro Heya et al. · Journal of Controlled Release · 1994 · 119 citations

Nanomedicine, Engineering, Micro-encapsulation +5

Pharmacokinetics of Once-a-Month Injectable Microspheres of Leuprolide Acetate

Hiroaki Okada, Yayoi Inoue, Toshiro Heya et al. · Pharmaceutical Research · 1991 · 114 citations