Pharmacokinetics of Once-a-Month Injectable Microspheres of Leuprolide Acetate

Leuprolide versus Diethylstilbestrol for Metastatic Prostate Cancer

New England Journal of Medicine · 1984 · 622 citations

Hormonal Contraceptive, Urology, Acid Phosphatase +10

A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid.

Yasuaki Ogawa, Masaki Yamamoto, Hiroaki Okada et al. · Chemical and Pharmaceutical Bulletin · 1988 · 502 citations · Full text

Engineering, Biomedical Engineering, Injectable Microcapsules +17

Controlled Release of LHRH Agonist, Leuprolide Acetate, from Microcapsules: Serum Drug Level Profiles and Pharmacological Effects in Animals

Yasuaki Ogawa, Hiroaki Okada, Toshiro Heya et al. · Journal of Pharmacy and Pharmacology · 1989 · 138 citations

Clinical Study of Leuprolide Depot Formulation in the Treatment of Advanced Prostate Cancer

ROOHOLIAH SHARIFI, Mark S. Soloway · The Journal of Urology · 1990 · 122 citations

One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats.

Hiroaki Okada, Toshiro Heya, Yuriko Ogawa et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 116 citations