Preparation of Three-Month Depot Injectable Microspheres of Leuprorelin Acetate Using Biodegradable Polymers

A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid.

Yasuaki Ogawa, Masaki Yamamoto, Hiroaki Okada et al. · Chemical and Pharmaceutical Bulletin · 1988 · 504 citations · Full text

Pharmacy, Bioengineering, Pharmaceutics +16

Lupron depot (leuprolide acetate for depot suspension) in the treatment of endometriosis: a randomized, placebo-controlled, double-blind study

Alexander M. Dlugi, James D. Miller, Judith Knittle · Fertility and Sterility · 1990 · 282 citations

Medicine, Gynecology, Pharmacotherapy +7

Preparation and in vitro degradation properties of polylactide microcapsules.

Kimiko Makino, Masayuki Arakawa, Tamotsu Kondo · Chemical and Pharmaceutical Bulletin · 1985 · 199 citations · Full text

Natural Sciences, Bioengineering, Materials Science +17

In vivo release profiles of leuprolide acetate from microcapsules prepared with polylactic acids or copoly(lactic/glycolic) acids and in vivo degradation of these polymers.

Yasuaki Ogawa, Hiroaki Okada, YASAKI YAMAMOTO et al. · Chemical and Pharmaceutical Bulletin · 1988 · 170 citations · Full text

Pharmacy, Bioengineering, Pharmaceutics +17

A randomized, placebo-controlled, double-blind study evaluating the efficacy of leuprolide acetate depot in the treatment of uterine leiomyomata

Andrew J. Friedman, Debra Harrison-Atlas, Robert L. Barbieri et al. · Fertility and Sterility · 1989 · 167 citations

Pharmacy, Gynecology, Pharmacotherapy +5