Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs

Jun-ichi Jinno, Naoki Kamada, Masateru Miyake, +7

Journal of Controlled Release

Poorly Water-soluble DrugParticle Size ReductionPharmacological StudyMedicineBeagle Dogs +2

Interleukin 6 and its relationship to clinical parameters in patients with malignant pleural mesothelioma

Takashi Nakano, A. Philippe Chahinian, Miho Shinjo, +5

British Journal of Cancer

InflammationMalignant Pleural MesotheliomaImmunologyPathologyPleural Disease +4

Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima

Hideyuki Ito, Masateru Miyake, Eisei Nishitani, +10

Cancer Letters

Tumor BiologyMedicinal ChemistryOncologyChemoprevention StrategyCowania Mexicana +10

In vitro–in vivo correlation for wet-milled tablet of poorly water-soluble cilostazol

Jun-ichi Jinno, Naoki Kamada, Masateru Miyake, +7

Journal of Controlled Release

Medicinal ChemistryPharmaceutical ScienceWet-milled TabletMedicineBioanalysis +7

Impact of the Dissolution Profile of the Cilostazol Cocrystal with Supersaturation on the Oral Bioavailability

Motoyasu Yoshimura, Masateru Miyake, Tatsuya Kawato, +5

Crystal Growth & Design

Medicinal ChemistryOral BioavailabilityCalculated SolubilityCilostazol CocrystalMedicine +8

Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: Utilization of polyamines and bile acids

Masateru Miyake, Takanori Minami, Masao Hirota, +5

Journal of Controlled Release

Pharmaceutical ScienceMedicineDigestive TractDrug AbsorptionPharmacology +3

Recent Advancements in the Development of Nanocarriers for Mucosal Drug Delivery Systems to Control Oral Absorption

Hideyuki Sato, Kohei Yamada, Masateru Miyake, +1

Pharmaceutics

NanoparticlesEngineeringMucus LayerOral AdministrationBiomedical Engineering +16

Prediction of drug intestinal absorption in human using the Ussing chamber system: A comparison of intestinal tissues from animals and humans

Masateru Miyake, Toshihisa Koga, Satoshi Kondo, +4

European Journal of Pharmaceutical Sciences

Gastrointestinal PharmacologyMedicineBioanalysisForensic ToxicologyGastroenterology +11

Establishment of Novel Prediction System of Intestinal Absorption in Humans Using Human Intestinal Tissues

Masateru Miyake, Hajime Toguchi, Toru Nishibayashi, +10

Journal of Pharmaceutical Sciences

Body CompositionHealth SciencesPhysiologyGastroenterologyNovel Prediction System +6

Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers

Fuyuki Mukaizawa, Koji Taniguchi, Masateru Miyake, +4

International Journal of Pharmaceutics

Pharmaceutical ScienceParacellular PathwaysBiochemistryCaco-2 Cell MonolayersMedicine +6