Keir J. Menzies

NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Hongbo Zhang, Dongryeol Ryu, Yibo Wu et al. · Science · 2016 · 1.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

Béatrice Chabi, Vladimir Ljubicic, Keir J. Menzies et al. · Aging Cell · 2007 · 432 citations · Full text

Medicine, Physiology, Aging +13

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Karim Gariani, Keir J. Menzies, Dongryeol Ryu et al. · Hepatology · 2015 · 359 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +17

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

Eija Pirinen, Carles Cantó, Young Suk Jo et al. · Cell Metabolism · 2014 · 253 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

NAD ⁺ repletion improves muscle function in muscular dystrophy and counters global PARylation

Dongryeol Ryu, Hongbo Zhang, Eduardo R. Ropelle et al. · Science Translational Medicine · 2016 · 251 citations · Full text

Life Sciences, Biochemistry, Physiology +16