Keir J. Menzies

NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Hongbo Zhang, Dongryeol Ryu, Yibo Wu et al. · Science · 2016 · 1.2K citations · Full text

Aging, Anti-aging, Cell Death +19

Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

Béatrice Chabi, Vladimir Ljubicic, Keir J. Menzies et al. · Aging Cell · 2007 · 427 citations · Full text

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Karim Gariani, Keir J. Menzies, Dongryeol Ryu et al. · Hepatology · 2015 · 353 citations · Full text

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

Eija Pirinen, Carles Cantó, Young Suk Jo et al. · Cell Metabolism · 2014 · 252 citations · Full text

Muscle Function, Muscle Injury, Mitochondrial Function +9

NAD ⁺ repletion improves muscle function in muscular dystrophy and counters global PARylation

Dongryeol Ryu, Hongbo Zhang, Eduardo R. Ropelle et al. · Science Translational Medicine · 2016 · 246 citations · Full text