Karim Gariani

NAD ⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

Hongbo Zhang, Dongryeol Ryu, Yibo Wu et al. · Science · 2016 · 1.2K citations · Full text

Aging, Anti-aging, Cell Death +19

De novo NAD+ synthesis enhances mitochondrial function and improves health

Elena Katsyuba, Adrienne Mottis, Marika Ziętak et al. · Nature · 2018 · 427 citations · Full text

Mitochondrial Function, Biochemistry, Mitochondrial Dynamic +8

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Karim Gariani, Keir J. Menzies, Dongryeol Ryu et al. · Hepatology · 2015 · 353 citations · Full text

NAD ⁺ repletion improves muscle function in muscular dystrophy and counters global PARylation

Dongryeol Ryu, Hongbo Zhang, Eduardo R. Ropelle et al. · Science Translational Medicine · 2016 · 246 citations · Full text

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

Partha Mukhopadhyay, Béla Horváth, Mohanraj Rajesh et al. · Journal of Hepatology · 2016 · 159 citations · Full text

Inflammation, Hepatology, Medicine +7