Lars Nærum

Improving the Odds in Discriminating “Drug-like” from “Non Drug-like” Compounds

Thomas M. Frimurer, Robert P. Bywater, Lars Nærum et al. · Journal of Chemical Information and Computer Sciences · 2000 · 123 citations

Machine Learning, Neural Network Prediction, Neural Network +19

Isoxazole-3-hydroxamic acid derivatives as peptide deformylase inhibitors and potential antibacterial agents

Lars Nærum, Seema Mukhija, Anders Hjelmencrantz · Bioorganic & Medicinal Chemistry Letters · 2004 · 83 citations

Biochemistry, Medicine, Natural Sciences +11

Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Lars J. S. Knutsen, Knud Erik Andersen, Jesper Lau et al. · Journal of Medicinal Chemistry · 1999 · 65 citations · Full text

Nipecotic Acid, Pharmacotherapy, Gaba Uptake Inhibitor +16

Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors

Lars Nærum, Leif Nørskov‐Lauritsen, Preben H. Olesen · Bioorganic & Medicinal Chemistry Letters · 2002 · 64 citations · Full text

Scaffold Hopping, Biochemistry, Protein Assembly +13

Efficient Generation, Storage, and Manipulation of Fully Flexible Pharmacophore Multiplets and Their Use in 3-D Similarity Searching

Edmond Abrahamian, Peter C. Fox, Lars Nærum et al. · Journal of Chemical Information and Computer Sciences · 2003 · 56 citations

Drug Target, Molecular Biology, Genomics +25