Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer

Lisa Derosa, Bertrand Routy, Andrew Maltez Thomas, +40

Nature Medicine

Pd-1 BlockadeMedicineImmunologyColorectal CancerPathology +7

Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

S.Y. Cindy Yang, Pauline Lejault, Sandy Chevrier, +4

Nature Communications

EngineeringMolecular BiologyGuanine-rich Rna SequencesTranscriptomics TechnologyTranscriptome-wide Identification +16

A Natural Polyphenol Exerts Antitumor Activity and Circumvents Anti–PD-1 Resistance through Effects on the Gut Microbiota

Meriem Messaoudene, Reilly Pidgeon, Corentin Richard, +29

Cancer Discovery

Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy

Jean-David Fumet, Corentin Richard, Fanny Ledys, +22

British Journal of Cancer

Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance

Antoine Bernard, Sandy Chevrier, Françoise Beltjens, +13

Cancer Research

AngiogenesisCaspase-3 Dna BindingCell SignalingCaspase-3-proficient CellsApoptosis +13

IRF8-dependent molecular complexes control the Th9 transcriptional program

Étienne Humblin, Marion Thibaudin, Fanny Chalmin, +11

Nature Communications

The transfer of multigene panel testing for hereditary breast and ovarian cancer to healthcare: What are the implications for the management of patients and families?

Marie Eliade, J. Skrzypski, Amandine Baurand, +24

Oncotarget

Family MedicineGenetic TestingBreast OncologyGeneticsGenetic Epidemiology +16

The expression of BIRC5 is correlated with loss of specific chromosomal regions in breast carcinomas

Romain Boidot, Frédérique Végran, Delphine Jacob, +7

Genes Chromosomes and Cancer

Breast OncologyApoptosis ProteinSpecific Chromosomal RegionsPathologyCancer Biology +16

The transcription factor GATA-1 is overexpressed in breast carcinomas and contributes to survivin upregulation via a promoter polymorphism

Romain Boidot, Frédérique Végran, Delphine Jacob, +5

Oncogene

MedicinePromoter PolymorphismBreast CancerBreast CarcinomasCell Biology +8

Exome Analysis Reveals Genomic Markers Associated with Better Efficacy of Nivolumab in Lung Cancer Patients

Corentin Richard, Jean-David Fumet, Sandy Chevrier, +9

Clinical Cancer Research