Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

Xiaoyang Lan, David J. Jörg, Florence M.G. Cavalli, +34

Nature

Neuro-oncologyEmbryonic Stem CellLineage PlasticityDevelopmental BiologyGlioma +9

Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma

Robert J. Vanner, Marc Remke, Marco Gallo, +25

Cancer Cell

BiologyCell LineageDevelopmental BiologyCell DivisionMorphogenesis +2

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

Nicole I. Park, Paul Guilhamon, Kinjal Desai, +24

Cell stem cell

ChromatinNeuro-oncologyGlioblastoma Stem CellsDevelopmental BiologyGlioma +11

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells

Sonam Dolma, Hayden Selvadurai, Xiaoyang Lan, +18

Cancer Cell

Neuro-oncologyGlioblastoma Stem CellsGliomaMedicineBrain-immune Interaction +5

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

Nishani Rajakulendran, Katherine Rowland, Hayden Selvadurai, +16

Genes & Development

Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma

Wen-Chi Yin, Thevagi Satkunendran, Rong Mo, +20

Developmental Cell

Functional GenomicsSignal TransductionDual Regulatory FunctionsGeneticsGene Regulation +7

Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor

Hayden Selvadurai, Erika Luis, Kinjal Desai, +15

Cell Reports

Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity

Xin Chen, Ali Momin, Siyi Wanggou, +34

Neuron

Neuro-oncologyBlood-tumor BarrierGliomaBlood–brain BarrierBiological Microenvironments +8

Wnt/β-catenin Signalling Is Active in a Highly Dynamic Pattern during Development of the Mouse Cerebellum

Hayden Selvadurai, John O. Mason

PLoS ONE

Mouse Cerebellum DevelopmentCellular NeurobiologySynaptic SignalingCellular PhysiologyTissue Development +23

Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt

Ahmed El‐Sehemy, Hayden Selvadurai, Arturo Ortín-Martínez, +8

Journal of Clinical Investigation

Gbm Stem CellsCancer BiologyGliomaGbm SubtypeTumor Biology +15